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The drug is a combination of drugs propranolol, hydrochlorothiazide and Trimateren. It is used for hypertension.
Cardiac output and blood pressure are constantly adjusted by a complicated system of several neurotransmitters from nerve signals to the body's needs. For example, ensures an increase in performance the hormone adrenaline. In the heart, is the coupling in certain binding sites, beta-receptors to where there is an increase in cardiac output and blood pressure. In the blood vessels that binds to receptors alpha and constricts blood vessels. Although this increase in blood pressure.
Propranolol is a beta-receptor blocker. It occupies the beta receptors and thus prevents the effects of adrenaline on the heart. The heart beats slower and less powerful, the blood pressure drops. The heart muscle uses less energy and oxygen - the adjustment of breath and heart pain, which occur when Herzenge (angina pectoris), are improved.
Hydrochlorothiazide and triamterene are diuretics (water pills): promote salt and water excretion by the kidneys. With decreasing water content in the blood, reduces the amount of blood pumped by the heart through the body. This relieves the heart and lowers blood pressure.
While hydrochlorothiazide resulted in increased excretion of potassium, slows triamterene and potassium in the body can compensate for the threat of loss of potassium. Potassium in the blood remains nearly the same. Way to avoid serious side effects such as muscle weakness and cardiac arrhythmias as a result of a potassium deficiency.
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