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Malarone is approved for the treatment and prevention of Plasmodium falciparum malaria in adults and children weighing al least 25lbs (11kg).
Malaria is indicate to prevent (prophylaxis of Plasmodium falciparum malaria), including in areas where chloroquine resistance has been reported, and to treat (treatment of acute, uncomplicated Plasmodium falciparum malaria).
The daily dose should be taken at the same time each day with food or milky drink, and repeat dose of Malarone if vomiting occurs within 1 hour after dosing.
Prevention of malaria: prophylactic treatment with Malarone should be started 1 or 2 days before entering a malaria-endemic area and continued daily during the stay and for 7 days return.
Adults: one Malarone tablet contains 250mg atovaquone/ 100mg proguanil hydrochloride
Pediatrics: one Malarone tablet contains 62.5mg atovaquone/ 25mg proguanil hydrochloride.
The dosage in pediatric patients is based upon body weight:
11-20 kg 1 daily, 21-30kg 2 as single dose daily, 31-40kg 3 as single dose daily, and more than 40kg 1 adult tablet daily.
Laboratory Malarone: GlaxoSmithKline
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